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Integrated precision for every LC–MS workflow

Flexible designs that deliver stable, high-performance nanoflow separations

Product Highlights

Robustness

Sensitivity

Next-generation integrated emitter technology delivers exceptional robustness, extended column lifetime, and enhanced analytical sensitivity.

Effortless

Integration

Versatile adapter compatibility enables plug-and-play usability across established LC–MS workflows, ensuring seamless workflow integration.

Performance

Accessibility

Delivering high-end performance at accessible pricing, providing reliable chromatographic solutions for laboratories of all scales.

Configurable

Selection

Available in lengths from 5 – 50 cm and inner diameters of 75 or 150 µm, with custom configurations available upon request.

Robustness

of column lifetime

ProtumLink’s column architecture combines the mechanical durability of traditional emitter-separate setups with the sensitivity and spray stability of integrated emitter designs. A reinforced packing bed and precisely shaped emitter tip maintain uniform flow and stable electrospray, supporting consistent performance over extended use. This integrated design reduces mechanical stress and minimizes signal fluctuations, resulting in longer column lifetimes and sustained analytical sensitivity, even in demanding high-throughput environments.

Image of an emitter

4 adapter types

Core

Blank Capillary Columns

Union

With Liquid Junctions (<1200bar)

Connect

With Liquid Junctions (<1200bar) and CSI-Adapter

Extend

Column cassette (< 1200bar) compatible with EASY-Spray™ Source

5 column lengths

5cm
8 cm
15cm
25cm
50cm

2 column diameters

75μm
150μm
Read more detail

Effortless

implementation

Our columns are designed to integrate smoothly into existing LC-MS setups. Users can choose from a range of adapter configurations, allowing direct compatibility with established laboratory hardware and workflows. This flexibility enables fast setup without extra investment or system modifications, supporting reliable plug-and-play operation for different platforms and application needs.

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Performance

of robust column set up

Performance chart

High-resolution peak separation is maintained across the different column lengths, demonstrating robust chromatographic performance of ProtumLink’s 75 µm ID designs. The presented FWHM values show narrow peak widths under commonly used injection amounts and gradient durations. This illustrates the expected separation efficiency for the respective setups and supports reliable identification depth and consistent quantification in routine proteomics.

Testimonials

Dr. Sarah Johnson

Senior Researcher at BioTech Labs

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Prof. Michael Chen

Laboratory Director at Research Institute

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Dr. Emily Rodriguez

Lead Scientist at Advanced Analytics

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Dr. James Park

Principal Investigator at Pharma Corp

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Application examples

Performance chart

Routine quality control measurements of 50 ng HeLa on a 25 cm × 75 µm Connect column with a 60 min gradient demonstrate highly consistent proteome depth across more than 700 LC-MS injections on a timsTOF HT system. Retention time coefficients of variation for precursor ions, assessed on randomly selected QC runs throughout the column lifetime, confirm excellent chromatographic stability, which is essential for reliable label-free quantification.

In cooperation with AG Warscheid, Lehrstuhl Biochemie II, Julius-Maximilians-Universität Würzburg.

Application Notes

Name of the document, can have many words as it might be a research document somehow

Doc - 5MB

Name of the document, can have many words as it might be a research document somehow

Doc - 5MB

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FAQ






Column Adapter Type

Core

Core

Emitter-integrated analytical columns designed for maximum flexibility in system configuration and custom workflows. Ideal for method development and broad instrument compatibility.

Union

Union

Emitter-integrated analytical columns featuring an integrated liquid junction for easy connection to standard nano-LC fittings.

Connect

Connect

Emitter-integrated analytical columns equipped with a Bruker CaptiveSpray adapter for native compatibility and true plug-and-play operation on timsTOF platforms.

Extend

Extend

Emitter-integrated analytical columns in a Thermo EasySpray compatible format using a pre-mounted emitter cassette design for simplified installation and reliable performance.

Core

Core

Emitter-integrated analytical columns designed for maximum flexibility in system configuration and custom workflows. Ideal for method development and broad instrument compatibility.

Union

Union

Emitter-integrated analytical columns featuring an integrated liquid junction for easy connection to standard nano-LC fittings.

Connect

Connect

Emitter-integrated analytical columns equipped with a Bruker CaptiveSpray adapter for native compatibility and true plug-and-play operation on timsTOF platforms.

Extend

Extend

Emitter-integrated analytical columns in a Thermo EasySpray compatible format using a pre-mounted emitter cassette design for simplified installation and reliable performance.

Explore Products

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© 2025 ProtumLink. All rights reserved.

ProtumLink

Find Us At

Location

Lutherstraße 150 07743 Jena, Germany

FacebookLinkedInYouTube

© 2025 ProtumLink. All rights reserved.