ProtumLink Extend 8cm

The 8 cm format provides additional resolving power over shorter columns while still supporting the speed needed for routine quantitative proteomics.

Measured at 800 nL/min, the column delivers consistent peak widths of ~3.4–4.2 s across 10–20 min gradients, offering focused peak geometry that improves duty-cycle efficiency and quantification reliability. This makes the format well suited for time-sensitive cohort studies and routine translational workflows.

An operational flow window of 100–1500 nL/min allows smooth movement between accelerated profiling and nanoflow-level sensitivity without system changes. The 8 cm length provides a practical balance of speed, resolving power, and robustness, making it suitable for laboratories running a broad mix of LC-MS assays.

Extend columns are supplied in a Thermo EasySpray-compatible cassette format, enabling direct installation on EasySpray ion sources without additional emitter hardware or external high-voltage components. Electrical contact and emitter alignment are established automatically through the cassette interface.

The Extend format follows widely used heater geometries, enabling compatibility with common external column heating systems.

At the inlet side, an integrated liquid junction allows straightforward connection to nano-LC systems using standard 10-32 threaded female fittings, enabling fast column exchange while preserving zero-dead-volume performance.

This configuration supports reliable nanospray performance, easy system setup, and seamless operation on Thermo Orbitrap platforms equipped with EasySpray sources.

• Thermo Scientific nanoViper Fingertight Fittings • IDEX Health & Science MarvelXACT UHPLC Connection Systems • Waters ZenFit Connection Technology (compatibility pending verification)